Thakur lab (2021-)

1. Heyt K# and Thakur J*. Role of non-coding RNAs in epigenetic processes. Nucleus (2021) Review article. (#Thakur lab undergraduate researcher, * Corresponding author).

2. Morrison O$, Thakur J*. Molecular Complexes at Euchromatin, Heterochromatin and Centromeric Chromatin. Int. J. Mol. Sci. 2021, 22(13), 6922 Review article. ($Thakur lab graduate student, * Corresponding author).

3. Thakur J*, Packiaraj J#, Henikoff S. Sequence, Chromatin and Evolution of Satellite DNA. Int. J. Mol. Sci. 2021, 22(9), 4309; Review article. (#Thakur lab undergraduate researcher, * Corresponding author).

Dr. Thakur’s post-doctoral work

1. Thakur J*, Henikoff S*. Architectural RNA in chromatin organization. Biochem Soc Trans. 2020 Sep 8; BST20191226. Review article. (*Corresponding author) Recommended by Quentin Vicens in Faculty Opinions (previously F1000 Prime).

2. Fang H, Bonora G, Lewandowski JP, Thakur J, Filippova GN, Henikoff S, Shendure J, Duan, John L. Rinn Z, Deng X, Noble WS, Disteche CM. Trans- and cis-acting effects of the lncRNA Firre on epigenetic and structural features of the inactive X chromosome. Nature Commun. 2020 Nov 27;11(1):6053.

3. Thakur J, Fang H, Llagas T, Disteche CM, Henikoff S. (2019) Architectural RNA is required for heterochromatin organization. biorxiv doi: Highlighted by Ramona Jühlen in “Cut the anchor: CUT&RUN.RNase identifies scaffolding of heterochromatic domains by RNA” in preLights Dec 2019

4. Thakur J , Henikoff S. (2018) Unexpected conformational variations of the human centromeric chromatin complex. Genes & Dev. 32:20-25

5. Henikoff S, Thakur J, Kasinathan S, Talbert PB. Remarkable evolutionary plasticity of centromeric chromatin. Cold Spring Harb Symp Quant Biol. 2017 Dec 1; Volume LXXXII

6. Thakur J, Henikoff S. (2016) CENP-T bridges adjacent CENP-A nucleosomes on young human α-satellite dimers. Genome Res. Sep;26(9):1178-87

7. Henikoff JG, Thakur J , Kasinathan S, Henikoff S. (2015) A unique chromatin complex occupies young α-satellite arrays of human centromeres. Sci Adv. Feb 12;1(1)

8. Thakur J, Talbert P, Henikoff S. (2015) Inner kinetochore protein interactions with regional centromeres of Fission Yeast. Genetics. Oct;201(2):543-61 Highlighted article

Dr Thakur’s doctoral work

1) Thakur J, Sanyal K. (2013) Efficient neocentromere formation is suppressed by gene conversion to maintain centromere function at native physical chromosomal loci in Candida albicans. Genome Res. Apr;23(4):638-52. Highlighted by Scott KC and Sullivan BA in “Neocentromeres: a place for everything and everything in its place” in Trends in Genetics (2014).

2) Thakur J, Sanyal K (2012) A coordinated interdependent protein circuitry stabilizes the kinetochore ensemble to protect CENP-A in the human pathogenic yeast Candida albicans. PLoS Genet.8(4):e1002661.

3) Thakur J, Sanyal K. (2011) The essentiality of the fungus-specific Dam1 complex is correlated with a one-kinetochore-one-microtubule interaction present throughout the cell cycle, independent of the nature of a centromere. Eukaryotic Cell. Oct;10(10):1295-305. Cover article

4) Padmanabhan S$, Thakur J , Siddharthan R, Sanyal K. (2008) Rapid evolution of Cse4p-rich centromeric DNA sequences in closely related pathogenic yeasts, Candida albicans and Candida dubliniensis. Proc Natl Acad Sci U S A. Dec 16;105(50):19797-802. $ S.P and $ J.T. equal contribution.

5) Sanyal K, Padmanabhan S, Thakur J (2016) Polynucleotide sequences of Candida dubliniensis and probes for detection. US Patent 9,334,535